PTEN is recognized as a prognostic-related biomarker and inhibits...
ObjectiveThis work aimed to examine the function of phosphatase and tensin homologue deleted on chromosome 10 (PTEN) in skull base chordoma (SBC) at the clinical and cellular levels.MethodsTotally 65...
View ArticleAn update on advanced therapies for Parkinson's disease: From gene therapy to...
Advanced Parkinson's disease (PD) is characterized by increasingly debilitating impaired movements that include motor fluctuations and dyskinesias. At this stage of the disease, pharmacological...
View ArticleImprovement of brain perfusion in patients with chronic brain ischemia at...
ObjectiveIncreasing life expectancy and aging of the population is accompanied by a steady increase in the number of elderly patients with chronic cerebral ischemia and age-related cognitive impairment...
View ArticlePeripheral blood eosinophil and classification of residual hematoma help...
Chronic subdural hematoma (CSDH) is a common type of intracranial hemorrhage in neurosurgical practice, whose incidence has increased markedly in recent years. However, CSDH still troubles clinicians...
View ArticleScalp block for postoperative pain after craniotomy: A meta-analysis of...
BackgroundPostoperative pain after craniotomy is an important clinical concern because it might lead to brain hyperemia and elevated intracranial pressure. Considering the side effects of opioid,...
View ArticleCase report: Epidural blood patches are effective in treating intracranial...
BackgroundIntracranial hypotension (IH) is usually associated with cerebrospinal fluid (CSF) leakage and/or CSF hypotension, and epidural blood patch (EBP) therapy has been proven to be effective for...
View ArticleTreatment of unruptured middle cerebral artery aneurysms: Systematic review...
ObjectiveOpen surgical clipping has been generally considered the best treatment option for unruptured middle cerebral artery aneurysms (uMCAAs). However, this type of aneurysm is being treated...
View ArticleIntegrated analysis of competitive endogenous ribose nucleic acids...
BackgroundThis study aims to identify the differentially expressed (DE) non-coding ribose nucleic acids (ncRNAs), messenger RNA (mRNA) expression profiles, and competitive endogenous RNA...
View ArticleQuality of life reporting in the management of posterior fossa tumours: a...
Introduction Survival amongst posterior fossa tumour (PFT) patients is improving. Clinical endpoints such as overall survival fail to depict QoL. There is yet to be a review of current QoL instruments...
View ArticleComparison of posterior decompression techniques and conventional laminectomy...
ObjectivesTo compare the efficacy of posterior decompression techniques with conventional laminectomy for lumbar spinal stenosis.MethodsThe Embase, PubMed, and Cochrane Library databases were searched...
View ArticleMultiple ossified spinal meningiomas in the thoracic spine: A case report and...
BackgroundOssified spinal meningioma (OSM) is a rare form of a spinal tumor. The surgical strategies and pathologic findings related to OSM have been investigated in recent years. However, multiple...
View ArticleCase Report: A case of cervical spinal epidural abscess combined with...
BackgroundSpinal epidural abscess (SEA) is a rare purulent infection of the central nervous system. Abscesses confined to the spinal canal can compress the spinal cord, causing nerve damage and even...
View ArticlePredictors of tumor progression of low-grade glioma in adult patients within...
BackgroundGlioma originates from glial cells in the brain and is the most common primary intracranial tumor. This study intends to use a retrospective analysis to explore the factors that can predict...
View ArticleA novel integrated angioscope-laser system for atherosclerotic carotid artery...
IntroductionAtherosclerotic extracranial carotid artery stenosis accounts for about 20%–30% of all strokes, which is one of the leading causes of adult morbidity and mortality. Although carotid...
View ArticleHyperkalemic cardiac arrest induced by mannitol administration during...
IntroductionMannitol is the most widely used hyperosmolar agent during neurosurgical procedures. However, its use can lead to serious hyperkalemia with altered cardiac conduction.Case presentationHere...
View ArticlePercutaneous fully endoscopic surgical management of the ruptured epidural...
BackgroundEpidural nerve block and analgesia are basic anesthetic techniques for anesthesia. Epidural catheter rupture and partial retention are adverse events and rare complications of epidural...
View ArticleAssociation between minimally invasive surgery and late seizures in patients...
PurposeThe association between minimally invasive surgery (MIS) for hematoma evacuation and late seizures after intracerebral hemorrhage (ICH) remains uncertain. We aimed to investigate whether MIS...
View ArticleThree-dimensional printing and 3D slicer powerful tools in understanding and...
With the development of the 3D printing industry, clinicians can research 3D printing in preoperative planning, individualized implantable materials manufacturing, and biomedical tissue modeling....
View ArticleA risk prediction model for evaluating thrombosis extension of muscle calf...
ObjectiveTo explore the risk factors of muscle calf venous thrombosis (MCVT) after craniotomy and construct a risk prediction model, so as to provide tool for evaluating the prognosis of MCVT after...
View ArticleIncidence of ischemic complications and technical nuances of arteries...
IntroductionInsular gliomas have complex anatomy and microvascular supply that make resection difficult. Furthermore, resection of insular glioma is associated with a significant risk of postoperative...
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